Avances en la Valoración de Macroalgas del Género Ulva como Nutracéutico en Litopenaeus vannamei
Palabras clave:
ulvaceas, camarón blanco del Pacifico, nutrición, antioxidanteResumen
Las algas marinas constituyen una fuente natural de antimicrobianos, antioxidantes, hepatoprotectores, inmunoestimulantes, minerales y prebióticos, que al ser suplementados (en forma de harina o extracto) como aditivos funcionales en alimentos para camarón pueden ayudar a promover la producción, la salud y aumentar la resistencia a enfermedades durante las diferentes etapas del cultivo (maduración, desarrollo larvario, engorda). El Programa Maricultura a través de su cuerpo académico ha promovido esta línea de investigación durante los últimos 3 años especialmente con el género Ulva. El objetivo de este trabajo es presentar una breve revisión de los efectos funcionales que hemos comprobado in vivo e in vitro, tales como: efecto antivibrio, antioxidante, promotor de maduración y sobrevivencia larvaria, estimulador de respuesta inmune y remediador contra aflatoxicosis y la estimación de contribuciones nutricionales a partir de análisis isotópicos.Descargas
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Abdel-Wahhab MA, Ahmed HH, Hagazi MM. 2006. Prevention of aflatoxin B1-initiated hepatotoxicity in rat by marine algae extracts. Journal of Applied Toxicology, 26(3), 229-238. doi: 10.1002/jat.1127.
Aguirre-Guzmán, G., Sánchez-Martinez, J. G., Campa-Córdova, A. I., Luna-González, A., & Ascencio, F. (2009). Penaeid shrimp immune system. Thai Journal of Veterinary and Medicine, 39(3), 205–215.
Bansemir A, Blume M , Schröder S , Lindequist, U. (2006). Screening of cultivated seaweeds for antibacterial activity against fish pathogenic bacteria. Aquaculture, 252(1), 79–84.
Barcelo A, Claustre J, Moro F, Chayvaille JA, Cuber JC, Plaisancie P. 2000. Muncin secretion is modulated by liminal factors in theisolated vascularly perfused rat colon. Gut 46: 218-224.
Batista González A. E., Charles M. B., Mancini-Filho J., Vidal Novoa A. 2009. Las algas marinas como fuente de fitofármacos antioxidantes. Revista Cubana de Plantas Medicinales. 14: 2-4
Berger, C. (2000) Aportes de la Biotecnología a la alimentación y a la inmunoestimulaciónde camarones peneidos. Asociación Langostina Peruana (ALPE). 102- 110.
Boonyaratpalin M, Supamattaya K, Verakunpiriya V, Suprasert D. 2001. Effects of aflatoxin B1 on growth performance, blood components, immune function and histopathological changes in black tiger shrimp (Penaeus monodon Fabricius). Aquaculture Research, 32, 388-398.
Burford, M.A., Preston, N.P., Minh, T.H., Hoa, T.T.T., Bunn, S.E., Fry, V.M. (2004) Dominant sources of dietary carbon and nitrogen for shrimp reared in extensive rice-shrimp ponds. Aquac. Res. 35, 194-203.
Cahu, C. (2000). Dietas para reproductores de camarón y su efecto en la calidad larvaria. In Civera-Cerecedo, R., Pérez-Estrada, C.J., Ricque-Marie, D. Cruz-Suárez L.E. (Ed.), Avances en Nutrición Acuícola IV. Memorias del IV Simposium Internacional de Nutrición Acuícola. Noviembre 15-18, 1998 (pp. 65–72). La Paz, B.C.S., México: Universidad Autónoma de Nuevo León.
Campa-Córdova, A. I., Hernández-Saavedra, N. Y., Aguirre-Guzmán, G., & Ascencio, F. (2005). Respuesta inmunomoduladora de la superóxido dismutasa en juveniles de camarón blanco (Litopenaeus vannamei) expuestos a inmunoestimulantes Immunomodulatory response of superoxide dismutase in juvenile American white shrimp (Litopenaeus vannamei) expos. Ciencias Marinas, 31(4), 661–669.
Campos Deloya M. T. (2012) Actividad antioxidante y bactericida contra Vibrios del extracto de Ulva clathrata . Tesis de licenciatura en Biología. 01/02/2013
Carrillo L. 2003. Microbiología agrícola. Facultad de Ciencias Agrarias de la Universidad Nacional de Salta: http://www. unsa. edu. ar/matbib.(02 06 2008).
Castro, R., Zarra, I., & Lamas, J. (2004). Water-soluble seaweed extracts modulate the respiratory burst activity of turbot phagocytes. Aquaculture, 229(1-4), 67–78. doi:10.1016/S0044-8486(03)00401-0
Castro, R., Piazzon, M. C., Zarra, I., Leiro, J., Noya, M., & Lamas, J. (2006). Stimulation of turbot phagocytes by Ulva rigida C. Agardh polysaccharides. Aquaculture, 254(1-4), 9–20. doi:10.1016/j.aquaculture.2005.10.012
Chakraborty K, Lipton AP, Paulraj R, Viajayan KK (2010) Antibacterial labdane diterpenoids of Ulva fasciata Delile from south western coast of the Indian Peninsula. Food Chem 119: 1399-1408. 12.
Chakraborty, K., Lipton, A. P., Paulraj, R., & Chakraborty, R. D. (2010). Guaiane sesquiterpenes from seaweed Ulva fasciata Delile and their antibacterial properties. European journal of medicinal chemistry, 45(6), 2237–44. doi:10.1016/j.ejmech.2010.01.065
Cheng, W., Liu, C.H., Yeh, S.T. & Chen, J.C. (2004). The immune stimulatory effect of sodium alginate on the white shrimp Litopenaeus vannamei and its resistence against Vibrio alginolyticus. Fish Shellfish Immunology, 17(1), 41-51.
Chi, Z.-M., Liu, G., Zhao, S., Li, J., & Peng, Y. (2010). Marine yeasts as biocontrol agents and producers of bio-products. Applied microbiology and biotechnology, 86(5), 1227–41. doi:10.1007/s00253-010-2483-9
Chiheb, I., Riadi, H., Martinez-Lopez, J., Dominguez-Seglar, J. F., Gomez-Vidal, J. A., Bouziane-Hassan, & Kadiri, M. (2009). Screening of antibacterial activity in marine green and brown macroalgae from the coast of Morocco. African Journal of Biotechnology, 8(7), 1258–1262. Retrieved from http://www.ajol.info/index.php/ajb/article/download/60101/48355
Christobel J.G., Lipton A.L., Aishwarya M.S., Sarika A.R. and Udayakumar A. 2011. Antibacterial activity of aqueous extract from selected macroalgae of southwest coast of India. Seaweed Res. Utiln. 33: 67-75.
Cruz-Suárez, L. E., et al., (2009). Use of seaweeds for shrimp nutrition: status and potential, The Rising Tide: Proceedings of the Special Session on Sustainable Shrimp Farming, The World Aquaculture Society. 131-141.
Cruz Suarez L.E., Campos Deloya M.T., Oranday A., Rivas C., Ricque D., 2014. Vibriocidal activity of Ulva clathrata extracts. En preparación.
Deachamag P., Intaraphad U., Phongdara A., Chotigeat W., 2006. Expression of a PhagocitosysActivating Protein (PAP) gene in immunized black tiger shrimp Aquaculture 255: 165-172.
DeNiro M.J., Epstein S. (1978) Influence of diet on the distribution of carbon isotope ratios in animals. Geochimica et Cosmochimica Acta 42, 495–506.
DeNiro M.J., Epstein S. (1981) Influence of diet on the distribution of nitrogen isotopes in animals. Geochimica et Cosmochimica Acta 45, 341–351.
Ehleringer, J.R., Rundel, P.W. (1989) Stable isotopes: History, units and instrumentation. In: Rundel, P.W., Ehleringr, J.R. and Nagy, K.A. (Eds) Stable Isotopes in Ecological Research. Springer- Verlag. New York. pp.1-16.
El-Baky, H.H.A., El-Baz, F.K., Baroty, G.S.E. 2008. Evaluation of Marine Alga Ulva lactuca as A Source of Natural Preservative Ingredient. American-Eurasian J. Agric. & Environ. Sci., 3 (3): 434-444.
Felix, S., Robins, P. H., & Rajeev, A. (2004a). Pro-PO based assessment of eco-friendly immunostimulation in Penaeus monodon (H . Milne Edwards). Indian J. Fish, 51(4), 401–405.
Felix, S., Robins, P. H., & Rajeev, A. (2004b). Immune enhancement assessment of dietry incorporated marine alga Sargassum wightii (Phaeophyceae / Punctariales) in tiger shrimp Penaeus monodon (Crustacia / Penaeidae) through prophenoloxidase (proPO) systems. Indian Journal of Marine Sciences, 33(December), 361–364.
Fu, Y.W., Hou, W.Y., Yeh, S.T., Li, C.H., & Chen, J.C. (2007). The immunostimulatory effects of hot-water extract of Gelidium amansii via immersion, injection and dietary administrations on white shrimp Litopenaeus vannamei and its resistance against Vibrio alginolyticus. Fish & shellfish immunology, 22(6), 673–85. doi:10.1016/j.fsi.2006.08.014
Gamboa-Delgado J., Cañavate J.P., Zerolo R., Le Vay L. (2008) Natural carbon stable isotope ratios as indicators of the relative contribution of live and inert diets to growth in larval Senegalese sole (Solea senegalensis). Aquaculture 280, 190-197.
Gamboa-Delgado J. (2009) Application of natural stable isotopes in aquaculture nutrition. PhD Thesis. University of Wales-Bangor, UK. 180 pp.
Gamboa-Delgado J., Le Vay L. (2009a) Natural stable isotopes as indicators of the relative contribution of soy protein and fish meal to tissue growth in Pacific white shrimp (Litopenaeus vannamei) fed compound diets. Aquaculture 291, 115-123.
Gamboa-Delgado J., Le Vay L. (2009b) Artemia replacement in co-feeding regimes for mysis and postlarval stages of Litopenaeus vannamei: Nutritional contribution of inert diets to tissue growth as indicated by natural carbon stable isotopes. Aquaculture 297, 128-135.
Gamboa-Delgado, J., Peña-Rodríguez, A., Cruz-Suárez, L.E., Ricque, D. (2011). Direct assessment of the nutritional contribution of co-fed live macroalgae Ulva clathrata and artificial feed to the growth of Pacific white shrimp (Litopenaeus vannamei). Journal of Shellfish Research, Vol. 30, No. 3, 1–10.
Ghaednia, B., Mehrabi, M. R., Mirbakhsh, M., Yeganeh, V., Hoseinkhezri, P., Garibi, G., & A, G. J. (2011). Effect of hot-water extract of brown seaweed Sargassum glaucescens via immersion route on immune responses of Fenneropenaeus indicus. Iranian Journal of Fisheries Sciencesdian Journal of Fisheries Sciences, 10(4), 616–630.
Gopinath R, Raj RP. 2009. Histological alterations in the hepatopancreas of Penaeus monodon Fabricius (1798) given aflatoxin B-1-incorporated diets. Aquaculture Research, 40(11), 1235-1242. doi: 10.1111/j.1365-2109.2009.02207.x
Gupta, S., & Abu-Ghannam, N. (2011). Recent developments in the application of seaweeds or seaweed extracts as a means for enhancing the safety and quality attributes of foods. Innovative Food Science & Emerging Technologies, 12(4), 600–609. doi:10.1016/j.ifset.2011.07.004
Hancock JT, Desikan R, Neill SJ. 2001. Role of reactive oxygen species in cell signalling pathways. Biochemical Society Transactions. 29 (2): 345–350.
Hayden, H. S., Blomster, J., Maggs, C. A., Silva, P. C., Stanhope, M. J., & Waaland, J. R. (2003). Linnaeus was right all along: Ulva and Enteromorpha are not distinct genera. European Journal of Phycology, 38(3), 277–294. doi:10.1080/1364253031000136321
Heo SJ, Park EJ, Lee KW, Jeon YJ. 2005. Antioxidant activities of enzymatic extracts from brown seaweeds.Bioresour Technol. 2005 Sep;96(14):1613-23.
Hose, J. E., Martin, G. G., & Gerard, A. S. (1990). A decapod hemocyte classification scheme integrating morphology, cytochemistry, and function. Biological Bulletin, 178(1), 33. doi:10.2307/1541535
Hou, W.Y. & Chen, J.C. 2005. The immunoestimulatoryeffect of the hot- water extract of Gracilaria tenuistipiata on the white shrimp Litopenaeus vannamei and its resistance against Vibrio alginolyticus. Fish Shellfish Immunol., 19(2), 127-138.
Huang, X., Zhou, H., & Zhang, H. (2006). The effect of Sargassum fusiforme polysaccharide extracts on vibriosis resistance and immune activity of the shrimp, Fenneropenaeus chinensis. Fish & shellfish immunology, 20(5), 750–7. doi:10.1016/j.fsi.2005.09.008
Immanuel, G., Vincybai, V., Sivaram, V., Palavesam, A, Marian, M. (2004). Effect of butanolic extracts from terrestrial herbs and seaweeds on the survival, growth and pathogen (Vibrio parahaemolyticus) load on shrimp Penaeus indicus juveniles. Aquaculture, 236(1-4), 53–65.
Immanuel, G., Sivagnanavelmurugan, M., Marudhupandi, T., Radhakrishnan, S., & Palavesam, A. (2012). The effect of fucoidan from brown seaweed Sargassum wightii on WSSV resistance and immune activity in shrimp Penaeus monodon (Fab). Fish & shellfish immunology, 32(4), 551–64. doi:10.1016/j.fsi.2012.01.003
Jomori R.K., Ducatti C., Carneiro D.J., Portella M.C. (2008) Stable carbon (δ13C) and nitrogen (δ15N) isotopes as natural indicators of live and dry food in Piaractus mesopotamicus (Holmberg, 1887) larval tissue. Aquaculture Research 39, 370–381.
Kabak B, Dobson AD, Var I. (2006). Strategies to prevent mycotoxin contamination of food and animal feed: a review. Critical Reviews in Food Science and Nutrition 46(8): 593–619.
Kaeffer, B., Bernard, C., Lahaye, M., Blottiere, H. M. & Cherbut, C. (1999). Biological properties of ulvan, a new source of green seaweed sulfated polysaccharides, on cultured normal and cancerous colonic epithelial cells. Planta Med. 65:527–31.
Kanjana, K., Radtanatip, T., Asuvapongpatana, S., Withyachumnarnkul, B., & Wongprasert, K. (2011). Solvent extracts of the red seaweed Gracilaria fisheri prevent Vibrio harveyi infections in the black tiger shrimp Penaeus monodon. Fish & shellfish immunology, 30(1), 389–96. doi:10.1016/j.fsi.2010.11.016
Kelman D, Posner EK, McDermid KJ, Tabandera NK, Wright PR, Wright AD. 2012. Antioxidant Activity of Hawaiian Marine Algae. Marine Drugs 10(6): 403-416.
Lahaye, M., & Robic, A. (2007). Structure and functional properties of Ulvan, a polysaccharide from green seaweeds. Biomacromolecules, 8(6), 1765–1774.
Lahaye, M., Inizan, F., & Vigouroux, J. (1998). NMR analysis of the chemical structure of ulvan and of ulvan–boron complex formation. Carbohydrate Polymers, 36, 239–249.
Leiro, J. M., Castro, R., Arranz, J. a, & Lamas, J. (2007). Immunomodulating activities of acidic sulphated polysaccharides obtained from the seaweed Ulva rigida C. Agardh. International immunopharmacology, 7(7), 879–88. doi:10.1016/j.intimp.2007.02.007
Lightner DV, Redman RM, Price RL, Wiseman MO. 1982. Histopathology of aflatoxicosis in the marine shrimp Penaeus stylirostris and P. vannamei. Journal of Invertebrate Pathology, 40(2), 279-291. doi: 10.1016/0022-2011(82)90127-6
Lu K., Lin W. & Liu J. 2008. The characteristics of nutrient removal and inhibitory effect of Ulva clathrata on Vibrio anguillarum 65. Journal of Applied Phycology. 20: 1061-1068.
Madhumathi, M. (2011). Antioxidant status of Penaeus monodon fed with Dunaliella salina supplemented diet and resistance against WSSV. International Journal of Engineering Science and Technology (IJEST), 3(10), 7249–7259
Manilal, A., Selvin, J., Sugathan, S., & Panikkar, M. V. N. (2012). Evaluation of therapeutic efficacy of indian green alga, Acrosiphonia orientalis (J. AGARDH) in the treatment of vibriosis in Penaeus monodon, Thalassas An International Journal of Marine Sciences, 28(January), 33–46.
Manoharan N, Sampathkumar P, Dheeba B, Sheikabdulla S, Vinothprasanna G. Vinothkannan R. Kalavathy S, Vijayaanand A, Shanmugasundaram A, 2008. Potential hepatoprotective effect of aqueous extract of Gracilaria corticata in AFB1 induced hepatotoxicity in Wistar Rats. Journal of Biological Sciencies 8 (8): 1352-1355.
McDermid, K. J., and Stuercke, B. (2003). Nutritional composition of edible Hawaiian seaweeds. Journal of Applied Phycology, 15(6), 513–524.
Mercado-Mercado, G., Carrillo, L. de la R., Wall-Medrano, A., López Díaz, J. A., and Álvarez-Parrilla, E. (2013). Compuestos polifenólicos y capacidad antioxidante de especias típicas consumidas en México. Nutrición hospitalaria, 28(1), 36–46. doi:10.3305/nh.2013.28.1.6298
Michener, R.H., Schell, D.M. (1994) Stable isotope ratios as tracers in marine aquatic food webs In: Stable isotopes in ecology and environmental science. Chapter 7. Vol 1 (ed. by Lajtha, K. and Michener, R.H.) Blackwell scientific publications. Oxford, UK. 138-157 pp.
Muñoz M, Cedeño R, Rodríguez J, Van der Knap WPW, Mialhe E, Bachère E. (2000). Measurement of reactive oxygen intermediate production in haemocytes of the penaeid shrimp, Penaeus vannamei. Aquaculture 191:89e107.
Nunes, A.J.P., Gesteira, T.C.V., Goddard, S. (1997) Food ingestion and assimilation by the Southern brown shrimp Penaeus subtilis under semi-intensive culture in NE Brazil. Aquaculture 149, 121–136.
Osman, M., Abu-Shady, A., & Elshobary, M. (2010). The seasonal fluctuation of the antimicrobial activity of some macroalgae collected from Alexandria coast, Egypt. researchgate.net. Retrieved from http://www.researchgate.net/publication/233726941_The_Seasonal_Fluctuation_of_the_Antimicrobi
al_Activity_of_Some_Macroalgae_Collected_from_Alexandria_Coast_Egypt/file/d912f50accd4b99b17.pdf
Paradossi, G., F. Cavalieri, L. Pizzoferrato and A.M. Liquori. 1999. A physico-chemical study on the polysaccharide ulvan from hot water extraction of the macroalga Ulva. International Journal of Biological Macromolecules 25:309-315.
Peterson, B.J., Fry, B. (1987) Stable isotopes in ecosystem studies. Annu. Rev. Ecol. Syst. 18, 293-320.
Priyadharshini, S., Bragadeeswaran, S., Prabhu, K., Ran, S. S. (2011). Antimicrobial and hemolytic activity of seaweed extracts Ulva fasciata (Delile 1813) from Mandapam, Southeast coast of India. Asian Pacific Journal of Tropical Biomedicine, 1(1), S38–S39
Qi H. Zhang Q, Zhao T, Hu R, Zhang K and Li Z. 2006. In vitro antioxidant activity of acetylated and benzoylated derivatives of polysaccharide extracted from Ulva pertusa (Chlorophyta). Bioor Med Chem. 16:2441-2445.
Qi, H., Zhao, T., Zhang, Q., Li, Z., Zhao, Z., Xing, R. (2006). Antioxidant activity of different molecular weight sulfated polysaccharides from Ulva pertusa Kjellm (Chlorophyta). Journal of Applied Phycology, 17(6), 527–534.
Ringø, E., Erik Olsen, R., Gonzalez Vecino, J. L., & Wadsworth, S. (2011). Use of immunostimulants and nucleotides in aquaculture: A Review. Journal of Marine Science: Research & Development, 02(01), 1–22. doi:10.4172/2155-9910.1000104
Rocha de Souza, M.C., C. Texeira-Masques, C.M. Guerra-Dore, F.R. Ferreira da Silva, H.A. Olivera-Rocha and E. Lisboa-Leite. (2007). Antioxidant activity of sulfated polysaccharides from brown and red seaweeds. Journal of Applied Phycology 19: 153–160.
Roseanu, A., Jecu, L., Badea, M., & Evans, R. W. (2010). Mycotoxins: An overview on their quantification methods. Romanian Journal of Biochemistry, 47(1), 79-86.
Ruperez, P., Ahrazem, O., Leal, A. (2002). Potential antioxidant capacity of sulphated polysaccharides from the edible marine brown seaweed Fucus vesiculosus. Journal of Agricultural and Food Chemistry, 50, 840–845.
Sánchez Campos, L. N., Díaz, F., Licea, A., Re, A. D., Lizárraga, M. L., Flores, M., Tordoya Romero, C. (2010). Effect of hydrosoluble polysaccharides of Macrocystis pyrifera on physiological and metabolic responses of Litopenaeus vannamei infected with Vibrio campbellii. Hidrobiologica, 20(3), 246–255.
Schlechtriem, C., Focken, U., Becker, K. (2004) Stable isotopes as a tool for nutrient assimilation studies in larval fish feeding on live food. Aquat. Ecol. 38, 93-100.
Schroeder, G.L. (1983) Sources of fish and prawn growth in polyculture ponds as indicated by δ13C analysis. Aquaculture 35, 29–42.
Selvin, J., Huxley, A. J., & Lipton, A. P. (2004). Immunomodulatory potential of marine secondary metabolites against bacterial diseases of shrimp. Aquaculture, 230(1-4), 241–248.
Selvin, J., & Lipton, A. P. (2004). Biopotentials of Ulva fasciata and Hypnea musclformis collected from the peninsular coast of India. Journal of Marine Science and Technology, 12(1), 1–6.
Selvin, J., Manilal, A., Sujith, S., Kiran, G. S., & Lipton, A. P. (2011). Efficacy of marine green alga Ulva fasciata extract on the management of shrimp bacterial diseases Eficacia del extracto del alga marina verde Ulva fasciata sobre el manejo de las enfermedades bacterianas en camarones. Lat. Am. J. Aquat. Res., 39(2), 197–204. doi:10.3856/vol39-issue2-fulltext-1
Seo MJ, Choi HS, Lee OH, Lee BY, 2013. Grateloupia lanceolata (Okamura) Kawaguchi, the edible red seaweed, inhibits lipid accumulation and reactive oxygen species production during differentiation in 3T3-L1 cells.Phytother Res. 7(5), 655-63. doi: 10.1002/ptr.4765.
Shanab S. M. M. (2007) Antioxidant and antibiotic activities of some seaweed (Egyptian Isolates). International J Agric & Biol.2:220-5.
Shen HM, Shi CY, Lee HP, Ong CN. 1994. Aflatoxin B1-induced lipid peroxidation in rat liver. Toxicology and Applied Pharmacology 127:145–150.
Shen HM, Ong CN, Shi CY. 1995. Involvement of reactive oxygen species in aflatoxin B1-induced cell injury in cultured rat hepatocytes.Toxicology 99:115–123.
Shen HM, Shi CY, Shen Y, Ong CN. 1996. Detection of elevated reactive oxygen species level in cultured rat hepatocytes treated with aflatoxin B1. Free Radical Biology and Medicine 21:139–146.
Silva M, Vieira L, Almeida AP, Kijjoa A. (2013). The marine macroalgae of the genus Ulva: chemistry, biological activities and potential pplications. Oceanography 1: 101. doi:10.4172/ocn.1000101
Silva, G. C., Albuquerque-Costa, R., Oliveira-Peixoto, J. R., Pessoa-Nascimento, F. E., Macedo-Carneiro, P. B. de, & Silva dis Fernandes-Vieira, R. H. (2013). Tropical Atlantic marine macroalgae with bioactivity against virulent and antibiotic resistant Vibrio. Latin American Journal of Aquatic Research, 41(1), 183–188.
Sirirustananun, N., Chen, J.-C., Lin, Y.-C., Yeh, S.-T., Liou, C.-H., Chen, L.-L., Sim, S. S., et al. (2011). Dietary administration of a Gracilaria tenuistipitata extract enhances the immune response and resistance against Vibrio alginolyticus and white spot syndrome virus in the white shrimp Litopenaeus vannamei. Fish & shellfish immunology, 31(6), 848–55. doi:10.1016/j.fsi.2011.07.025
Smith, V. J., Brown, J. H., & Hauton, C. (2003). Immunostimulation in crustaceans: does it really protect against infection? Fish & Shellfish Immunology, 15(1), 71–90. doi:10.1016/S1050-4648(02)00140-7
Sohal RS, Weindruch R. 1996.Oxidative stress, caloric restriction, and aging.Science. 273 (5271): 59–63.
Tan, S. P., O’Sullivan, L., Prieto, M. L., Gardiner, G. E., Lawlor, P. G., Leonard, F., Duggan P., McLoughlin P., Hughes, H. (2011). Extraction and bioautographic-guided separation of antibacterial compounds from Ulva lactuca. Journal of Applied Phycology, 24(3), 513–523. doi:10.1007/s10811-011-9747-3.
Tapia-Salazar M, García-Pérez OD, Velásquez-Soto RA, Nieto-López MG, Villarreal-Cavazos D, Ricque-Marie D, Cruz-Suárez LE. 2012. Growth, feed intake, survival, and histological response of white shrimp Litopenaeus vannamei fed diets containing grains naturally contaminated with aflatoxin. Cienc. Mar. 38: 491–504.
Tayag, C. M., Lin, Y.-C., Li, C.-C., Liou, C.-H., & Chen, J.-C. (2010). Administration of the hot-water extract of Spirulina platensis enhanced the immune response of white shrimp Litopenaeus vannamei and its resistance against Vibrio alginolyticus. Fish & shellfish immunology, 28(5-6), 764–73. doi:10.1016/j.fsi.2010.01.023
Trigui, M., Gasmi, L., Zouari, I., & Tounsi, S. (2012). Seasonal variation in phenolic composition, antibacterial and antioxidant activities of Ulva rigida (Chlorophyta) and assessment of antiacetylcholinesterase potential. Journal of Applied Phycology, 25(1), 319–328. doi:10.1007/s10811-012-9866-5
Van der Zanden, M.J., Shuter, B.J., Lester N., Rasmussen. J.B. (1999) Patterns of food chain lengths in lakes: A stable isotope study. Am. Nat. 154, 406–416.
Verschoor A.M., Boonstra H., Meijer T. (2005) Application of stable isotope tracers to studies of zooplankton feeding, using the rotifer Brachionus calyciflorus as an example. Hydrobiologia, 546, 535–5
Wang L, Piao X L, Kim S W, Piao X S, Shen Y B, Lee H S.(2008). Effects of Forsythia suspensa extract on growth performance, nutrient digestibility, and antioxidant activities in broiler chickens under high ambient temperature. Poultry Science, 87, 1287-1294.
Xue, Z., C.H. Xue, Z.J. Li, Y.P. Cai, H.Y. Liu and H.T. Qi. (2004). Antioxidant and hepatoprotective activities of low molecular weight sulfated polysaccharide from Laminaria japonica. Journal of Applied Phycology., 16: 111–5
Yeh ST, Lee CS, Chen JC (2006) Administration of hot-power extract of brown seaweed Sargassum duplicatum via immersion and injection enhances the immune resistenace of white shrimp Litopenaeus vannamei. Fish Shellfish Immunol 20:332-345.
Yildiz, G., Celikler, S., Vatan, O., Dere, S. (2012). Determination of the antioxidative capacity and bioactive compounds in green seaweed Ulva rigida C. Agardh. International Journal of Food Properties, 15(6), 1182–1189.
Zubia, M., Robledo, D., & Freile-Pelegrin, Y. (2007). Antioxidant activities in tropical marine macroalgae from the Yucatan Peninsula, Mexico. Journal of Applied Phycology, 19(5), 449–458. doi:10.1007/s10811-006-9152-5
