Effects of nutritional status and environmental factors on the endocrine regulation of feeding in freshwater fish


  • Helene Volkoff University of Newfoundland

Palabras clave:

endocrine regulation, freshwater fish


In fish, food intake is ultimately regulated by feeding centers of the brain, which receive and process information from endocrine signals from both brain and peripheral tissues such as the gastrointestinal tract. These endocrine signals induce [orexigenic, such as orexin, neuropeptide Y (NPY) and ghrelin] or inhibit  [anorexigenic, such as cocaine and amphetamine regulated transcript (CART), leptin, peptide Y (PYY), cholecystokinin (CCK), proopiomelanocortin (POMC)] food intake, and maintain energy homeostasis (1, 2). Levels of energy stores, feeding status (e.g. fasting) and diet composition, as well as environmental conditions (e.g. temperature, pH, oxygen levels) influence feeding and the expression of endocrine appetite regulators.


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Volkoff, H. (2019) Fish as models for understanding the vertebrate endocrine regulation of feeding and weight. Molecular and Cellular Endocrinology, 497, 110437.

Ronnestad, I., A.S. Gomes, K. Murashita, R. Angotzi, E. Jonsson, and H. Volkoff (2017) Appetite-controlling endocrine systems in teleosts. Frontiers in Endocrinology, 8, 73.

Bertucci, J.I., A.M. Blanco, L. Sundarrajan, J.J. Rajeswari, C. Velasco, and S. Unniappan (2019) Nutrient regulation of endocrine factors influencing feeding and growth in fish. Frontiers in Endocrinology, 10.

Butt, Z.D., E. O'Brien, and H. Volkoff (2019) Effects of fasting on the gene expression of appetite regulators in three Characiformes with different feeding habits (Gymnocorymbus ternetzi, Metynnis argenteus and Exodon paradoxus). Comparative Biochemistry and Physiology A, 227, 105-115.

Pitts, P.M. and H. Volkoff (2017) Characterization of appetite-regulating factors in platyfish, Xiphophorus maculatus (Cyprinodontiformes Poeciliidae). Comparative Biochemistry and Physiology A, 208, 80-88.

Peyon, P., H. Saied, X. Lin, and R.E. Peter (1999) Postprandial, seasonal and sexual variations in cholecystokinin gene expression in goldfish brain. Molecular Brain Research, 74(1), 190-196.

Feng, K., G.-r. Zhang, K.-j. Wei, B.-x. Xiong, T. Liang, and H.-c. Ping (2012) Molecular characterization of cholecystokinin in grass carp (Ctenopharyngodon idellus): cloning, localization, developmental profile, and effect of fasting and refeeding on expression in the brain and intestine. Fish Physiology and Biochemistry, 38(6), 1825-1834.

Volkoff, H., R. Estevan Sabioni, L.L. Coutinho, and J.E.P. Cyrino (2017) Appetite regulating factors in pacu (Piaractus mesopotamicus): Tissue distribution and effects of food quantity and quality on gene expression. Comparative Biochemistry and Physiology A, 203, 241-254.

Volkoff, H., R.E. Sabioni, and J.E.P. Cyrino (2016) Appetite regulating factors in dourado, Salminus brasiliensis: cDNA cloning and effects of fasting and feeding on gene expression. General and Comparative Endocrinology, 237, 34-42.

Narnaware, Y.K. and R.E. Peter (2002) Influence of diet composition on food intake and neuropeptide Y (NPY) gene expression in goldfish brain. Regulatory Peptides, 103(2), 75-83.

Librán-Pérez, M., I. Geurden, K. Dias, G. Corraze, S. Panserat, and J.L. Soengas (2015) Feeding rainbow trout with a lipid-enriched diet: effects on fatty acid sensing, regulation of food intake and cellular signaling pathways. Journal of Experimental Biology, 218(16), 2610-2619.

Volkoff, H., Feeding and its regulation, in Climate Change and Non-infectious Fish Disorders, P.T.K. Woo and G.K. lwama, Editors. 2020, CABI (Centre for Agriculture and Biosciences International): Oxfordshire, United Kingdom.

Volkoff, H. and I. Rønnestad (2020) Effects of temperature on feeding and digestive processes in fish. Temperature, 7(4), 307-320.

Nadermann, N., R.K. Seward, and H. Volkoff (2019) Effects of potential climate change -induced environmental modifications on food intake and the expression of appetite regulators in goldfish. Comparative Biochemistry and Physiology A, 235, 138-147.

Vikeså, V., L. Nankervis, and E.M. Hevrøy (2017) Appetite, metabolism and growth regulation in Atlantic salmon (Salmo salar L.) exposed to hypoxia at elevated seawater temperature. Aquaculture Research, 48(8), 4086–4101.

Kullgren, A., F. Jutfelt, R. Fontanillas, K. Sundell, L. Samuelsson, K. Wiklander, P. Kling, W. Koppe, D.G.J. Larsson, B.T. Bjornsson, and E. Jonsson (2013) The impact of temperature on the metabolome and endocrine metabolic signals in Atlantic salmon (Salmo salar). Comparative Biochemistry and Physiology A, 164(1), 44-53.

Lemly, A.D. and R.J.F. Smith (1987) Effects of chronic exposure to acidified water on chemoreception of feeding stimuli in fathead minnows (Pimephales promelas): Mechanisms and ecological implications. Environmental Toxicology and Chemistry, 6(3), 225-238.

Mustapha, M.K. and S.D. Atolagbe (2018) Tolerance level of different life stages of Nile tilapia Oreochromis niloticus (Linnaeus, 1758) to low pH and acidified waters. The Journal of Basic and Applied Zoology, 79(1), 46.

Tix, J.A., C.T. Hasler, C. Sullivan, J.D. Jeffrey, and C.D. Suski (2017) Elevated carbon dioxide has the potential to impact alarm cue responses in some freshwater fishes. Aquatic Ecology, 51(1), 59-72.

Heuer, R.M. and M. Grosell (2014) Physiological impacts of elevated carbon dioxide and ocean acidification on fish. American Journal of Physiology - Regulatory, Integrative and Comparative Physiology, 307(9), R1061.

Abdel-Tawwab, M., M.N. Monier, S.H. Hoseinifar, and C. Faggio (2019) Fish response to hypoxia stress: growth, physiological, and immunological biomarkers. Fish Physiology and Biochemistry, 45(3), 997-1013.

Bernier, N.J., M. Gorissen, and G. Flik (2012) Differential effects of chronic hypoxia and feed restriction on the expression of leptin and its receptor, food intake regulation and the endocrine stress response in common carp. Journal of Experimental Biology, 215(13), 2273-2282.

Chu, D.L.H., V.W.T. Li, and R.M.K. Yu (2010) Leptin: Clue to poor appetite in oxygen-starved fish. Molecular and Cellular Endocrinology, 319(1), 143-146.

Kestemont, P. and E. Baras (2001) Environmental Factors and Feed Intake: Mechanisms and Interactions. Food Intake in Fish, 131-156.

Conde-Sieira, M., M. Chivite, J.M. Míguez, and J.L. Soengas (2018) Stress effects on the mechanisms regulating appetite in teleost fish. Frontiers in Endocrinology, 9.




Cómo citar

Volkoff, H. (2022). Effects of nutritional status and environmental factors on the endocrine regulation of feeding in freshwater fish. Avances En Nutrición Acuicola, 1(1), 113–117. Recuperado a partir de https://nutricionacuicola.uanl.mx/index.php/acu/article/view/359